HCID 54282362, compound → HCID 53898882, compound

Participants

Reaction Steps

A crude product was obtained in the same manner as in Example 8 except for using 3-(3-(4,4-bis(diethoxyphosphinoyl)butyrylamino)-4-hydroxyphenyl)-4-(4-hydroxyphenyl)-3-hexene (0.48 g) obtained by the process described in Example 32, and then it was purified by a high-performance reversed phase column chromatography (a 0.1% aqueous trifluoroacetic acid solution:acetonitrile) to obtain 3-(3-(4,4-diphosphonobutyrylamino)-4-hydroxyphenyl)-4-(4-hydroxyphenyl)-3-hexene (74 mg, yield 19%).

Provenance & Evidence