Phenacyl bromide → HCID 381511, compound

HRID 1737292Notes

Reaction equation

HRID 1737292 reaction equation
[Cl:1][C:2]1[C:3](=[O:14])[O:4][C:5]2[C:10]([C:11]=1[CH3:12])=[CH:9][CH:8]=[C:7]([OH:13])[CH:6]=2.Br[CH2:16][C:17]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)=[O:18]>>[Cl:1][C:2]1[C:3](=[O:14])[O:4][C:5]2[CH:6]=[C:7]([O:13][CH2:16][C:17]3([C:19]4[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=4)[O:18][C:5](=[O:4])[C:10](=[CH2:9])[CH2:11]3)[CH:8]=[CH:9][C:10]=2[C:11]=1[CH3:12]

Participants

3

Reactant 2

HCID 6259Phenacyl bromideHCID 53550793-Chloro-7-hydroxy-4-methyl-2-benzopyrone

Product 1

HCID 381511HCID 381511, compoundYield 71%

Procedure

Compound 7 was prepared from 3-chloro-7-hydroxy-4-methylcoumarin and 2-bromoacetophenone according to the procedure given for 4, yield: 71%;

Sources & evidence

ORD record
ord-1c79d358c8704283a33c6f40f5267d9a
Source dataset
uspto-grants-1999_10
Patent number
US05962460

Reaction notes

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