Ethoxyacetic acid → HCID 22611317, compound

HRID 1738023Notes

Reaction equation

HRID 1738023 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1.[CH2:18]([O:20][CH2:21][C:22](O)=[O:23])[CH3:19]>>[CH2:18]([O:20][CH2:21][C:22]([NH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1)=[O:23])[CH3:19]

Participants

3

Reactant 2

HCID 12301Ethoxyacetic acidHCID 118312203-(1-Methylpiperidin-4-yl)-1h-indol-5-amine

Product 1

HCID 22611317HCID 22611317, compoundYield 97%

Procedure

Beginning with 12.0 mg (0.05 mMol) 5-amino-3-(1-methylpiperidin-4-yl)-1H-indole and 11.0 μL (0.10 mMol) ethoxyacetic acid, 15.2 mg (97%) of the title compound were recovered.

Sources & evidence

ORD record
ord-2303283ce8734d61bbaf089c2c5b35cb
Source dataset
uspto-grants-1999_10
Patent number
US05962473

Reaction notes

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