Sulfuryl chloride → HCID 15672346, compound

HRID 1738364Notes

Reaction equation

HRID 1738364 reaction equation
S(Cl)([Cl:4])(=O)=O.[Cl:6][C:7]1[C:12]([CH3:13])=[CH:11][C:10]([C:14]2[CH:18]=[C:17]([O:19][CH:20]([F:22])[F:21])[N:16]([CH3:23])[N:15]=2)=[C:9]([F:24])[CH:8]=1.C(=O)([O-])O.[Na+]>ClC(Cl)(Cl)Cl>[Cl:4][C:18]1[C:14]([C:10]2[CH:11]=[C:12]([CH3:13])[C:7]([Cl:6])=[CH:8][C:9]=2[F:24])=[N:15][N:16]([CH3:23])[C:17]=1[O:19][CH:20]([F:22])[F:21]

Participants

5

Reactant 3

HCID 24648Sulfuryl chlorideHCID 516892Sodium BicarbonateHCID 15030566HCID 15030566, compound

Product 1

HCID 15672346HCID 15672346, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

22 g (0.16 mol) of sulfuryl chloride were added dropwise to a solution of 43 g (0.15 mol) of 3-(4-chloro-2-fluoro-5-methylphenyl)-5-difluoromethoxy-1-methyl-1H-pyrazole in 250 ml of tetrachloromethane. After the reaction solution had subsequently been stirred for 16 hours, 200 ml of saturated aqueous sodium hydrogen carbonate solution were added dropwise. The organic phase was thereupon separated off, washed using saturated sodium chloride solution, dried over magnesium sulfate, then filtered and subsequently concentrated. Yield: 46 g.

Workup

  1. customThe organic phase was thereupon separated off
  2. washwashed
  3. dry with materialdried over magnesium sulfate
  4. filtrationfiltered
  5. concentrationsubsequently concentrated

Sources & evidence

ORD record
ord-0baeda6bf46d410596f94cd257768349
Source dataset
uspto-grants-1999_10
Patent number
US05962694

Reaction notes

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