Dimethylformamide → HCID 22998514, compound

HRID 1738425Notes

Reaction equation

CN(C=O)C.[S:6]([Cl:10])(Cl)(=[O:8])=[O:7].[CH2:11]([C:15]1[S:19][C:18]2[CH:20]=[CH:21][CH:22]=[CH:23][C:17]=2[CH:16]=1)[CH2:12][CH2:13][CH3:14]>>[CH2:11]([C:15]1[S:19][C:18]2[CH:20]=[CH:21][CH:22]=[CH:23][C:17]=2[C:16]=1[S:6]([Cl:10])(=[O:8])=[O:7])[CH2:12][CH2:13][CH3:14]

Participants

Reactant 3

HCID 6228Dimethylformamide

HCID 24648Sulfuryl chloride

HCID 106553122-Butyl-1-benzothiophene

Product 1

HCID 22998514HCID 22998514, compound

Procedure

2-n-Butylbenzo[b]thiophene-3-sulfonyl chloride was prepared by the method of Example 40B with DMF (6.6 mmoles, 0.51 ml), sulfuryl chloride (5.6 mmoles, 0.45 ml) and 2-n-butylbenzo[b]thiophene (3.3 mmoles, 0.63 g). Flash chromatography (2% ethyl acetate/hexanes) provided 0.68 g (71%) of an orange solid.

Sources & evidence

ORD record: ord-8c81bfcf0079435390d7a0b2ce15d566
Source dataset: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05962490

Reaction notes

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