Benzyl Bromide → 3-benzylthiophene

HRID 1738516Notes

Reaction equation

HRID 1738516 reaction equation
[S:1]1[CH:5]=[CH:4][C:3](B(O)O)=[CH:2]1.[CH2:9](Br)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[CH2:9]([C:3]1[CH:4]=[CH:5][S:1][CH:2]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 581760Thiophene-3-boronic acid

Product 1

HCID 104874713-benzylthiopheneYield 74%

Procedure

3-benzylthiophene was prepared in the same manner as described in Example 32C using 3-thienylboronic acid and benzyl bromide, 74% yield.

Sources & evidence

ORD record
ord-c82cc84378aa48e3bf2d8b20d09ec4da
Source dataset
uspto-grants-1999_10
Patent number
US05962490

Reaction notes

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