4-t-Butylbenzenesulfonyl chloride → Benzenesulfonamide

HRID 1738651Notes

Reaction equation

HRID 1738651 reaction equation
C([C:5]1[CH:10]=[CH:9][C:8]([S:11](Cl)(=[O:13])=[O:12])=[CH:7][CH:6]=1)(C)(C)C.[N:15]1C=CC=CC=1.C1(C)C=CC=CC=1>>[C:8]1([S:11]([NH2:15])(=[O:13])=[O:12])[CH:9]=[CH:10][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 1398824-t-Butylbenzenesulfonyl chlorideHCID 22007288Pyridine toluene

Product 1

HCID 7370Benzenesulfonamide

Procedure

Reaction with p-tert-butylbenzenesulphonyl chloride in pyridine/toluene at room temperature yielded pure 4-tert-butyl-N-[3-(2-tetrahydropyranyloxyethoxy)-2-methoxy-phenoxy)-phenyl]-benzenesulphonamide. MS: Mt /e=555.

Sources & evidence

ORD record
ord-18a535080f7247fd8430b79d0b11a6e1
Source dataset
uspto-grants-1999_10
Patent number
US05962682

Reaction notes

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