反应详情

To 150 ml of acetone were suspended 20 g of 5-bromosalicylaldehyde, 22.9 g of 2-bromo-4-methoxyacetophenone and 27.6 g of anhydrous potassium carbonate. After stirring at room temperature for 4 hours, the resulting reaction solution was concentrated to dryness, and then mixed with water to collect precipitated crystals by filtration. After washing with water and subsequent recrystallization from ethanol, 14.02 g of 5-bromo-2-(4-methoxybenzoyl)benzofuran was obtained in the form of colorless prism crystals.

1. customthe resulting reaction solution
2. concentrationwas concentrated to dryness
3. additionmixed with water
4. customto collect
5. customprecipitated crystals
6. filtrationby filtration
7. washAfter washing with water and subsequent recrystallization from ethanol