1,2,3,4-Tetrahydro-1-naphthylamine → Adenine hydrochloride

Participants

Reaction Steps

A solution of 6-chloropurine (1.546 g, 10 mM) and 1-aminotetralin(1.472 g, 10 mM) in isopropanol (60 ml) is heated to reflux for about 20 h. The resulting salt suspension is then cooled to room temperature, filtered and the residue washed with ice-cooled isopropanol to give almost pure title compound in 80% yield.

Provenance & Evidence