Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Trifluoromethanesulfonic anhydride | HCID 67749 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 1-Trityl-4-(4-cyanobenzyl)imidazole | HCID 15837533 | — |
| Reactant | HCID 21840018 | HCID 21840018 | — |
| Product | HCID 21840022 | HCID 21840022 | — |
Reaction Steps
The product from Step F (1 eq) and the product from Example 1, Step E (1 eq) were dissolved in methylene chloride containing diisopropylethylamine , cooled to -78° C. under argon and treated with trifluoromethane sulfonic anhydride as described in Example 1, Step F. After methanolysis, the title compound was isolated by chromatography on silica gel.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05965578 |
|---|
| Source dataset | uspto-grants-1999_10 |
|---|
| ORD ID | ord-dce2448bf81e470d9fde87f4d0315b61 |
|---|
| Source note | uspto-grants-1999_10 |
|---|
