HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiazolidinedione → 5-[4-(4-Isopropoxyphenyl)butyl]-2,4-thiazolidinedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiazolidinedione | HCID 5437 | — |
| Reactant | 2-[3-(4-Isopropoxyphenyl)propyl]-1,3-dioxolane | HCID 10868709 | — |
| Product | 5-[4-(4-Isopropoxyphenyl)butyl]-2,4-thiazolidinedione | HCID 10935716 | 68% |
Reaction Steps
According to the same manner as that described in Example 23, 2-[3-(4-isopropoxyphenyl)propyl]-1,3-dioxolane was condensed with 2,4-thiazolidinedione, and the resulting compound was subjected to catalytic hydrogenation to give crystals of 5-[4-(4-isopropoxyphenyl)butyl]-2,4-thiazolidinedione (yield: 68%). This product was recrystallized from ether-hexane. Colorless prisms, mp: 72-73° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05965589 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-30f192a5467b486f84c2fe2079947922 |
| Source note | uspto-grants-1999_10 |