Diisobutylaluminumhydride → HCID 11084708, compound

HRID 1739033Notes

Reaction equation

[CH:1]([O:4][C:5]1[CH:17]=[CH:16][C:8]([CH:9]=[CH:10][C:11](OCC)=[O:12])=[CH:7][CH:6]=1)([CH3:3])[CH3:2].[H-].C([Al+]CC(C)C)C(C)C>>[CH:1]([O:4][C:5]1[CH:17]=[CH:16][C:8](/[CH:9]=[CH:10]/[CH2:11][OH:12])=[CH:7][CH:6]=1)([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 21225700Diisobutylaluminumhydride

HCID 54119352HCID 54119352, compound

Product 1

HCID 11084708HCID 11084708, compound

Procedure

According to the same manner as that described in Reference Example 10, ethyl 4-isopropoxycinnamate was reduced with diisobutyl aluminum hydride to give (E)-3-(4-isopropoxyphenyl)-2-propenol as an oil. This oil was purified by column chromatography on silica gel (eluent: ethyl acetate-hexane (1:4, v/v)) (yield: 83%).

Sources & evidence

ORD record: ord-b0375b4162f34d26a68474a95d04a71a
Source dataset: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05965589

Reaction notes

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