HCID 11118803, compound → HCID 10998484, compound

HRID 1739034Notes

Reaction equation

[CH:1]([O:4][C:5]1[CH:10]=[CH:9][C:8](/[CH:11]=[CH:12]/[CH:13]=[CH:14]/[C:15](OCC)=[O:16])=[CH:7][CH:6]=1)([CH3:3])[CH3:2].[H-].C([Al+]CC(C)C)C(C)C>>[CH:1]([O:4][C:5]1[CH:10]=[CH:9][C:8](/[CH:11]=[CH:12]/[CH:13]=[CH:14]/[CH2:15][OH:16])=[CH:7][CH:6]=1)([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 11118803HCID 11118803, compound

HCID 21225700Diisobutylaluminumhydride

Product 1

HCID 10998484HCID 10998484, compoundYield 76%

Procedure

According to the same manner as that described in Reference Example 10, ethyl (E,E)-5-(4-isopropoxyphenyl)-2,4-pentadienoate was reduced with diisobutyl aluminum hydride to give crystals of (E,E)-5-(4-isopropoxyphenyl)-2,4-pentadienol (yield: 76%). The crystals were recrystallized from isopropyl ether. Colorless needles, mp: 91-92° C.

Sources & evidence

ORD record: ord-d32ad856f75d475fbf9b33ce6222e8bf
Source dataset: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05965589

Reaction notes

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