Thionyl Chloride → 4-(3-Phenylpropyloxy)benzylchloride

Participants

Reaction Steps

3.0 g of 4-(3-phenylpropyloxy)benzyl alcohol were dissolved in 30 ml of chloroform, and 1.77 g of thionyl chloride were further fed dropwise to the resultant solution. The solution was then stirred for 1 hour at room temperature. After completed the reaction, the solution reacted was poured into ice-water and extracted with chloroform. The organic layer resulted was dried with anhydrous magnesium sulfate, and the solvent used was distillated under reduced pressure, thereby affording 3.2 g of 4-(3-phenylpropyloxy)benzylchloride.

Provenance & Evidence