Thionyl Chloride → HCID 21841066, compound

HRID 1739406Notes

Reaction equation

HRID 1739406 reaction equation
[C:1]1([CH3:20])[CH:6]=[CH:5][C:4]([O:7][CH2:8][CH2:9][CH2:10][O:11][C:12]2[CH:19]=[CH:18][C:15]([CH2:16]O)=[CH:14][CH:13]=2)=[CH:3][CH:2]=1.S(Cl)([Cl:23])=O>C(Cl)(Cl)Cl>[C:1]1([CH3:20])[CH:6]=[CH:5][C:4]([O:7][CH2:8][CH2:9][CH2:10][O:11][C:12]2[CH:19]=[CH:18][C:15]([CH2:16][Cl:23])=[CH:14][CH:13]=2)=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 53631983HCID 53631983, compound

Product 1

HCID 21841066HCID 21841066, compoundYield 106.6%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

1.67 g of 4-[3-(4-tolyloxy)propyloxy]benzyl alcohol were dissolved in 30 ml of chloroform, and the resultant solution was then stirred for 1 hour at room temperature after conducting the dropping of 0.88 g of thionyl chloride into the solution. The solution reacted was then poured into ice-water and extracted with chloroform, and the organic layer resulted was dried with anhydrous magnesium sulfate, and the solvent used was removed by distillation under reduced pressure thereby affording 1.9 g of 4-[3-(4-tolyloxy)propyloxy]benzyl chloride.

Workup

  1. customThe solution reacted
  2. extractionextracted with chloroform
  3. customthe organic layer resulted
  4. dry with materialwas dried with anhydrous magnesium sulfate
  5. customthe solvent used was removed by distillation under reduced pressure

Sources & evidence

ORD record
ord-db3cc80377f1440aa764466205ac543b
Source dataset
uspto-grants-1999_10
Patent number
US05965743

Reaction notes

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