反应详情

A solution of 2-amino-5-ethyl-1,3,4-thiadiazole (42.6 g) and 4-iodobenzyl bromide (89.1 g) in ethanol (500 ml) was heated under reflux for 20 hours. After the reaction mixture was cooled, the crystals so precipitated were collected by filtration and then dried, whereby 83 g of the title compound was obtained.

1. temperatureunder reflux for 20 hours
2. temperatureAfter the reaction mixture was cooled
3. customthe crystals so precipitated
4. filtrationwere collected by filtration
5. customdried