反应详情

A solution of 1-benzylpiperazine (5 g, 28.4 mmol) and sulphamide (2.77 g) in 1,4-dioxane (25 ml) was heated under reflux for 24 hours. The solution was cooled and poured into water (100 ml). The solid was filtered off, washed with toluene (100 ml) and dried under reduced pressure to give the title compound (4.75 g).

1. temperatureunder reflux for 24 hours
2. temperatureThe solution was cooled
3. filtrationThe solid was filtered off
4. washwashed with toluene (100 ml)
5. customdried under reduced pressure