HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 86754624, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (+/-)-trans-6-(3-Bromophenyl)-1,2,3,4,4a,5,6,7,8,8a-decahydro-2-ethyl-4a-(3-methoxyphenyl)-6-isoquinolinol | HCID 86754623 | — |
| Product | Ammonium Hydroxide | HCID 14923 | — |
| Product | HCID 86754624 | HCID 86754624 | 118.4% |
Reaction Steps
The reaction was conducted as described in Example 2, using 0.44 g (0.99 mmol) of (±)-trans-6-(3-bromophenyl)-1,2,3,4,4a,5,6,7,8,8a-decahydro-2-ethyl-4a-(3-methoxyphenyl)-6-isoquinolinol and 15 ml of 37% HCl. The crude reaction mixture was purified by flash chromatography, eluting with a mixture CH2Cl2 /MeOH/conc. NH4OH 98:2:0.4 respectively, yielding 0.25 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05968949 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-637aa65fceed4eb7826e910f57122ee6 |
| Source note | uspto-grants-1999_10 |