Ethanol → HCID 15338403, compound

HRID 1740268Notes

Reaction equation

HRID 1740268 reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]([Cl:12])([Cl:11])[C:8]([OH:10])=[O:9].[CH2:13](O)[CH3:14]>Cl>[CH2:13]([O:9][C:8](=[O:10])[C:7]([Cl:11])([Cl:12])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][Br:1])[CH3:14]

Participants

4

Reactant 2

HCID 702EthanolHCID 15338398HCID 15338398, compound

Product 1

HCID 15338403HCID 15338403, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Conditions

Temperature
0 °C

Procedure

19.5 g 5 was dissolved in 300 ml ethanol, saturated at 0° C. with hydrochloric acid gas and stirred for a further 5 hours at 0° C. After removing the major amount of ethanol in a vacuum, the residue was taken up in ether, washed with water, dried over magnesium sulfate and the solvent was removed. 21.2 g (98%) 7-bromo-2,2-dichloroheptanoic acid ethyl ester 6 was obtained as a colourless oil.

Workup

  1. customAfter removing the major amount of ethanol in a vacuum
  2. washwashed with water
  3. dry with materialdried over magnesium sulfate
  4. customthe solvent was removed

Sources & evidence

ORD record
ord-4e10ee798bbe40ada3f3379d2a90d6f8
Source dataset
uspto-grants-1999_10
Patent number
US05968982

Reaction notes

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