Dichloroacetic Acid → HCID 10620734, compound

HRID 1740269Notes

Reaction equation

Br[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][O:12][C:13]1[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=1.[Cl:20][CH:21]([Cl:25])[C:22]([OH:24])=[O:23]>>[Cl:20][C:21]([Cl:25])([CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][O:12][C:13]1[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=1)[C:22]([OH:24])=[O:23]

Participants

Reactant 2

HCID 6597Dichloroacetic Acid

HCID 10521631HCID 10521631, compound

Product 1

HCID 10620734HCID 10620734, compoundYield 50%

Procedure

Analogously to the preparation of 62, 13.6 g (65%) 63 was obtained from 7.7 g (60 mmol) 4-chlorophenol and 18 g (60 mmol) 1,10-dibromodecane. 13.3 g (38.0 mmol) 63 was reacted with dichloroacetic acid according to example 9. 5.9 g (50%) 11, melting point 63-64° C. was obtained.

Sources & evidence

ORD record: ord-bd191b3bde6245b6814ab59bb6aff12a
Source dataset: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05968982

Reaction notes

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