反应详情

温度

60 °C

To a solution of 10.70 g of 1-tert-butoxycarbonyl-4-(2-(2-propynyl)ethyl)piperazine in 1,4-dioxane was added 4N hydrochloric acid/1,4-dioxane, and the mixture was stirred at 60° C. After completion of the reaction, the mixture was concentrated and diethyl ether was added. The solid was collected by filtration and dried to give 11.83 g of the title compound.

1. customAfter completion of the reaction
2. concentrationthe mixture was concentrated
3. additiondiethyl ether was added
4. filtrationThe solid was collected by filtration
5. customdried