HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 1-(2-(2-Propynyloxy)ethyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1-(2-(2-Propynyloxy)ethyl)piperazine dihydrochloride | HCID 21838637 | — |
| Product | 1-(2-(2-Propynyloxy)ethyl)piperazine | HCID 21838638 | 37.4% |
Reaction Steps
To an aqueous solution of 11.83 g of 1-(2-(2-propynyloxy)ethyl)piperazine dihydrochloride (water: 10 mL) was added aqueous sodium hydroxide solution, and the mixture was extracted with ethyl acetate. The organic layer was dried over anhydrous magnesium sulfate and evaporated to give 3.09 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05969138 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-43fb667518ee413291bef76ce4c8c4a7 |
| Source note | uspto-grants-1999_10 |