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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1740390Generated: October 25, 2026

1-(2-(2-Propynyloxy)ethyl)piperazine → 1-(4-Chlorophenyl)-3-(4-(2-(2-propynyloxy)ethyl)piperazin-1-yl)methyl-2-pyrrolidinone

https://huagongshe.com/reaction/1740390

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-(2-Propynyloxy)ethyl)piperazineHCID 21838638—
Reactant1-(4-Chlorophenyl)-3-mesyloxymethyl-2-pyrrolidinoneHCID 21838640—
Product1-(4-Chlorophenyl)-3-(4-(2-(2-propynyloxy)ethyl)piperazin-1-yl)methyl-2-pyrrolidinoneHCID 21838652—

Reaction Steps

The title compound was prepared from 1-(4-chlorophenyl)-3-mesyloxymethyl-2-pyrrolidinone and 1-(2-(2-propynyloxy)ethyl)piperazine, in the same manner as in Preparation Example 1(8).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05969138
Source datasetuspto-grants-1999_10
ORD IDord-5bd40fc376bd4e20b511500991d4fcc3
Source noteuspto-grants-1999_10