HuagongsheHuagongshe Chemistry Print Report · For research reference only
(-)-Mandelic acid → HCID 131721410, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (-)-Mandelic acid | HCID 11914 | — |
| Reactant | 1-(4-Chlorophenyl)-3-(4-(2-methoxyethyl)piperazin-1-yl)methyl-2-pyrrolidinone | HCID 4913209 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 131721410 | HCID 131721410 | — |
Reaction Steps
To a hot solution of 66.6 g of 1-(4-chlorophenyl)-3-(4-(2-methoxyethyl)piperazin-1-yl)methyl-2-pyrrolidinone in 350 mL of ethyl acetate was added a hot solution of (R)-(-)-mandelic acid in 120 mL of ethyl acetate. After cooling, the precipitated crystals were filtered, washed with ethyl acetate and dried in vacuo to give 36.4 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05969138 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-863b5d1590384cdd894169d67c9fd564 |
| Source note | uspto-grants-1999_10 |