HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-mandelic acid → HCID 131721411, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-mandelic acid | HCID 439616 | — |
| Reactant | 1-(4-Chlorophenyl)-3-(4-(2-methoxyethyl)piperazin-1-yl)methyl-2-pyrrolidinone | HCID 4913209 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 131721411 | HCID 131721411 | 35.7% |
Reaction Steps
Under heating, 152 mg of (S)-(+)-mandelic acid was added to a solution of 352 mg of 1-(4-chlorophenyl)-3-(4-(2-methoxyethyl)piperazin-1-yl)methyl-2-pyrrolidinone in 3 mL of ethyl acetate. After cooling, the precipitated crystals were filtered and dried in vacuo to give 180 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05969138 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-2f91f5c76c964de38b9388afdd7a8b4e |
| Source note | uspto-grants-1999_10 |