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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1740404Generated: October 30, 2026

MS-377 free base → HCID 86754639, compound

https://huagongshe.com/reaction/1740404

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMS-377 free baseHCID 9892249—
ReactantHydroxybenzenesulfonic acidHCID 15619088—
SolventEthanolHCID 702—
ProductHCID 86754639HCID 86754639154.3%

Reaction Steps

To a solution of 176 mg of benzenesulfonic acid monohydrate in 10 mL of ethanol was added a solution of 352 mg of (R)-1-(4-chlorophenyl)-3-(4-(2-methoxyethyl)piperazin-1-yl)methyl-2-pyrrolidinone in 10 mL of ethanol. The mixture was concentrated. The residue was sludged with ethanol. The solid formed was filtered and dried to give 407 mg of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05969138
Source datasetuspto-grants-1999_10
ORD IDord-0ab2c4fd4869408dac0b5a45956d19f5
Source noteuspto-grants-1999_10