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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1740405Generated: October 31, 2026

MS-377 free base → HCID 86754640, compound

https://huagongshe.com/reaction/1740405

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMS-377 free baseHCID 9892249—
ReactantHydroxybenzenesulfonic acidHCID 15619088—
SolventEthyl AcetateHCID 8857—
ProductHCID 86754640HCID 8675464087.6%

Reaction Steps

To a solution of 352 mg of benzenesulfonic acid monohydrate in 10 mL of ethyl acetate was added a solution of 352 mg of (R)-1-(4-chlorophenyl)-3-(4-(2-methoxyethyl)piperazin-1-yl)methyl-2-pyrrolidinone in 10 mL of ethyl acetate. The mixture was stirred at room temperature and cooled. The precipitated solid was filtered and dried to give 585 mg of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05969138
Source datasetuspto-grants-1999_10
ORD IDord-8d110df5684a415094d23f7d5d7c361c
Source noteuspto-grants-1999_10