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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1740407Generated: October 28, 2026

Methanesulfonic Acid → HCID 86754642, compound

https://huagongshe.com/reaction/1740407

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanesulfonic AcidHCID 6395—
ReactantMS-377HCID 9892249—
SolventEthyl AcetateHCID 8857—
ProductHCID 86754642HCID 8675464279.7%

Reaction Steps

A solution of 240 mg of methanesulfonic acid in 5 mL of ethyl acetate was added to a solution of 880 mg of (R)-1-(4-chlorophenyl)-3-(4-(2-methoxyethyl)piperazin-1-yl)methyl-2-pyrrolidinone in 15 mL of ethyl acetate. The mixture was stirred at room temperature and cooled. The precipitated solid was filtered and dried to give 892 mg of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05969138
Source datasetuspto-grants-1999_10
ORD IDord-eb2a2379b311423a993de556c5f36a35
Source noteuspto-grants-1999_10