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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1740408Generated: October 31, 2026

Methanesulfonic Acid → HCID 86754643, compound

https://huagongshe.com/reaction/1740408

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanesulfonic AcidHCID 6395—
ReactantMS-377 free baseHCID 9892249—
SolventEthyl AcetateHCID 8857—
ProductHCID 86754643HCID 8675464382.9%

Reaction Steps

A solution of 480 mg of methanesulfonic acid in 5 mL of ethyl acetate was added to a solution of 880 mg of (R)-1-(4-chlorophenyl)-3-(4-(2-methoxyethyl)piperazin-1-yl)methyl-2-pyrrolidinone in 15 mL of ethyl acetate. The mixture was stirred at room temperature and cooled. The precipitated solid was filtered and dried to give 1127 mg of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05969138
Source datasetuspto-grants-1999_10
ORD IDord-23cad752b9e64390833c7aca00b19962
Source noteuspto-grants-1999_10