HuagongsheHuagongshe Chemistry Print Report · For research reference only
Fumaric Acid → HCID 86754647, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Fumaric Acid | HCID 444972 | — |
| Reactant | MS-377 free base | HCID 9892249 | — |
| Solvent | Water ethanol | HCID 19096565 | — |
| Product | HCID 86754647 | HCID 86754647 | 89.8% |
Reaction Steps
Into 62 mL of 13% water-ethanol were suspended 5.00 g of (R)-1-(4-chlorophenyl)-3-(4-(2-methoxyethyl)piperazin-1-yl)methyl-2-pyrrolidinone and 3.30 g of fumaric acid. After making it homogeneous by heating under reflux, the solution was cooled. The precipitated solid was filtered and dried to give 7.45 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05969138 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-624079f5019e44d79dbaa7c88fd3b10c |
| Source note | uspto-grants-1999_10 |