Potassium Carbonate → HCID 21833033, compound

Participants

Reaction Steps

4-(2-Dimethylaminoethyl)-2,3,4,6-tetrahydropyrrolo[2,3-g][1,4]benzoxazine (D18, 42 mg, 0.17 mmol) was stirred in acetic acid (5 ml) as sodium cyanoborohydride (33 mg, 0.52 mmol) was added portionwise over 10 min. The mixture was stirred for 2 h, diluted with water, basified with potassium carbonate, and extracted with ethyl acetate. The extract was dried (Na2SO4) and evaporated to give the title compound (34 mg, 80%) as a green gum.

Provenance & Evidence