HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 1-Isopropylpiperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 1-[4-(Propan-2-yl)piperazin-1-yl]ethan-1-one | HCID 18796419 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-Isopropylpiperazine | HCID 78013 | 105.7% |
Reaction Steps
A mixture of 7.26 g of 1-acetyl-4-isopropylpiperazine, 100 ml of methanol and 10 g of potassium hydroxide was heated under reflux for 17 hours. After the solvent was distilled off, water and chloroform were added to perform extraction with chloroform and the extract was dried over anhydrous magnesium sulfate. The solvent was distilled off under reduced pressure to afford 5.78 g of the title compound as an oily substance.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05972943 |
| Source dataset | uspto-grants-1999_10 |
| ORD ID | ord-93506c81b4994fe99c541d2a852aa260 |
| Source note | uspto-grants-1999_10 |