Benzyl Alcohol → 2-Pyridinamine, 4-methyl-N-(phenylmethyl)-

HRID 1740930Notes

Reaction equation

[NH2:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][N:3]=1.[OH-].[K+].[CH2:11](O)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[CH2:11]([NH:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][N:3]=1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

Reactant 3

HCID 244Benzyl Alcohol

HCID 15332-Amino-4-methylpyridine

HCID 14797Potassium Hydroxide

Product 1

HCID 830532-Pyridinamine, 4-methyl-N-(phenylmethyl)-

Procedure

2-Amino-4-methylpyridine was reacted with potassium hydroxide in benzyl alcohol according to the method of Sprinzak (Org. Syn. Coll. Vol. IV. 91 (1963)) to form the title compound.

Sources & evidence

ORD record: ord-bfc10614764841c5b75c8c2406d2e572
Source dataset: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05972975

Reaction notes

Loading…