HCID 21834421, compound → HCID 21834443, compound

HRID 1740936Notes

Reaction equation

HRID 1740936 reaction equation
[N+:1]([C:4]1[C:5]([CH3:17])=[CH:6][C:7]([NH:10][C:11](=[O:16])[C:12]([CH3:15])([CH3:14])[CH3:13])=[N:8][CH:9]=1)([O-])=O>C(O)(=O)C>[NH2:1][C:4]1[C:5]([CH3:17])=[CH:6][C:7]([NH:10][C:11](=[O:16])[C:12]([CH3:13])([CH3:14])[CH3:15])=[N:8][CH:9]=1

Participants

3

Reactant 1

HCID 21834421HCID 21834421, compound

Product 1

HCID 21834443HCID 21834443, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of 5-nitro-4-methyl-2-trimethylacetylaminopyridine (4.5 g, 18.97 mmol) in 50 mL of acetic acid containing 10% palladium/carbon was hydrogenated at atmospheric pressure for 48 h. The catalyst was removed by filtration and the filtrate was concentrated. The residue was coevaporated with toluene to give the title compound.

Workup

  1. customThe catalyst was removed by filtration
  2. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-e6fb60bf14fb4c2cb7d7927070233025
Source dataset
uspto-grants-1999_10
Patent number
US05972975

Reaction notes

Loading…