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Potassium Hydroxide → 2-Amino-4-methyl-6-(2-phenylethyl)pyridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | Hydroxyamine hydrochloride | HCID 443297 | — |
| 反応物 | 4-Methyl-2-(2,5-dimethylpyrrol-1-yl)-6-(2-phenylethyl)pyridine | HCID 21834429 | — |
| 溶媒 | Water ethanol | HCID 19096565 | — |
| 生成物 | 2-Amino-4-methyl-6-(2-phenylethyl)pyridine | HCID 9920769 | — |
反応手順
By analogy to Example 56, Step B, 4-methyl-2-(2,5-dimethylpyrrol-1-yl)-6-(2-phenylethyl)pyridine was treated with 4.6 equivalents of hydroxylamine hydrochloride and 2.8 equivalents of potassium hydroxide in refluxing ethanol/water to yield 2-amino-4-methyl-6-(2-phenylethyl)pyridine as a colorless oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05972975 |
| 出典データセット | uspto-grants-1999_10 |
| ORD ID | ord-e4a03b5712e04e35898eadd280eebc6a |
| 出典メモ | uspto-grants-1999_10 |