Hydrochloric Acid → HCID 9834715, compound

Participants

Reaction Steps

A mixture of methyl 5-(6-amino-4-methyl-2-pyridinyl)pentanoate (119 mg, 0.536 mmol) in 10 mL of 2.0 N hydrochloric acid was refluxed for 3 h. After cooling to room temperature, the reaction was extracted with 2×10 mL of dichloromethane and the aqueous phase was concentrated in vacuo to give 134 mg of 5-(6-amino-4-methyl-2-pyridinyl)pentanoic acid hydrochloride as a pink solid.

Provenance & Evidence