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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1741049Generated: October 26, 2026

2-(4-Bromo-3-methylphenyl)-5-methyl-1,3,4-oxadiazole → 2,2'-Dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxylic acid

https://huagongshe.com/reaction/1741049

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Bromo-3-methylphenyl)-5-methyl-1,3,4-oxadiazoleHCID 11436693—
Reactant4-Borono-3-methylbenzoic acidHCID 22115892—
Product2,2'-Dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxylic acidHCID 21833769—

Reaction Steps

The title compound was prepared from 2-(4-bromo-3-methylphenyl)-5-methyl-1,3,4-oxadiazole (EP 0533268 A1) and 4-borono-3-methylbenzoic acid (D33) using a similar procedure to Description 11 as a white solid (31%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05972951
Source datasetuspto-grants-1999_10
ORD IDord-a62c4f55da3546a38b9f69d5afbfb2eb
Source noteuspto-grants-1999_10