Hydrochloric Acid → HCID 21833811, compound

HRID 1741073Notes

Reaction equation

HRID 1741073 reaction equation
[Br:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=1[CH3:10].[CH3:11][OH:12].[ClH:13]>C(OCC)C>[ClH:13].[Br:1][C:2]1[CH:9]=[CH:8][C:5]([C:6](=[NH:7])[O:12][CH3:11])=[CH:4][C:3]=1[CH3:10]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 27374944-Bromo-3-methylbenzonitrile

Product 1

HCID 21833811HCID 21833811, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

4-Bromo-3-methylbenzonitrile (15.0 g, 76.5 mmol) was dissolved in dry methanol (3.1 ml, 76.5 mmol) and dry diethyl ether (108 ml), cooled to 0-5°, then saturated with HCl (g). Stirred for 18 hours at room temperature and the solid collected by filtration, then dried in vacuo to yield the title compound as white needle-like crystals (19.3 g, 95%).

Workup

  1. filtrationthe solid collected by filtration
  2. customdried in vacuo

Sources & evidence

ORD record
ord-6fc91bcd584d45b7b987e4ba9d6c7711
Source dataset
uspto-grants-1999_10
Patent number
US05972951

Reaction notes

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