HRID1741096

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10657952

未命名化合物

结构：Cc1cc(-c2noc(N(C)C)n2)ccc1-c1ccc(C(=O)O)cc1

HCID21833846

未命名化合物

PRODUCTS

生成物

结构：Cc1cc(-c2noc(N(C)C)n2)ccc1-c1ccc(C(=O)N2CCc3cc4c(cc32)C2(CCN(C)CC2)CO4)cc1

HCID21833798

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 1'-methyl-2,3,6,7-tetrahydrospiro [furo[2,3-f]indole-3,4'-piperidine] (D8) and 4'-(5-dimethylamino-1,2,4-oxadiazol-3-yl)-2'-methylbiphenyl-4-carboxylic acid (D14) using a procedure similar to that of Example 1 (18%). This was converted to the oxalate salt, which precipitated from acetone/ether as a white solid.

WORKUP

后处理

customprecipitated from acetone/ether as a white solid

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c28a8d472480470388fa213cbeb2b796
来源数据集: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05972951
来源说明: uspto-grants-1999_10

反应 SMILES

[CH3:1][N:2]1[CH2:7][CH2:6][C:5]2([C:18]3[C:10](=[CH:11][C:12]4[CH2:13][CH2:14][NH:15][C:16]=4[CH:17]=3)[O:9][CH2:8]2)[CH2:4][CH2:3]1.[CH3:19][N:20]([CH3:42])[C:21]1[O:25][N:24]=[C:23]([C:26]2[CH:31]=[CH:30][C:29]([C:32]3[CH:37]=[CH:36][C:35]([C:38](O)=[O:39])=[CH:34][CH:33]=3)=[C:28]([CH3:41])[CH:27]=2)[N:22]=1>>[CH3:19][N:20]([CH3:42])[C:21]1[O:25][N:24]=[C:23]([C:26]2[CH:31]=[CH:30][C:29]([C:32]3[CH:37]=[CH:36][C:35]([C:38]([N:15]4[C:16]5[CH:17]=[C:18]6[C:5]7([CH2:8][O:9][C:10]6=[CH:11][C:12]=5[CH2:13][CH2:14]4)[CH2:4][CH2:3][N:2]([CH3:1])[CH2:7][CH2:6]7)=[O:39])=[CH:34][CH:33]=3)=[C:28]([CH3:41])[CH:27]=2)[N:22]=1