HRID1741097

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10657952

未命名化合物

结构：Cc1nc(-c2ccc(-c3ccc(C(=O)O)cc3)cc2)no1

HCID21833757

4'-(5-Methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-carboxylic acid

C16H12N2O3

PRODUCTS

生成物

结构：Cc1nc(-c2ccc(-c3ccc(C(=O)N4CCc5cc6c(cc54)C4(CCN(C)CC4)CO6)cc3)cc2)no1

HCID21833792

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 1'-methyl-2,3,6,7-tetrahydrospiro [furo[2,3-f]indole-3,4'-piperidine] (D8) and 4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxylic acid (D15), using a procedure similar to that of Example 1 (57%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ed35fa5d8fc94c9284edd5dcd8f82519
来源数据集: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05972951
来源说明: uspto-grants-1999_10

反应 SMILES

[CH3:1][N:2]1[CH2:7][CH2:6][C:5]2([C:18]3[C:10](=[CH:11][C:12]4[CH2:13][CH2:14][NH:15][C:16]=4[CH:17]=3)[O:9][CH2:8]2)[CH2:4][CH2:3]1.[CH3:19][C:20]1[O:24][N:23]=[C:22]([C:25]2[CH:30]=[CH:29][C:28]([C:31]3[CH:36]=[CH:35][C:34]([C:37](O)=[O:38])=[CH:33][CH:32]=3)=[CH:27][CH:26]=2)[N:21]=1>>[CH3:1][N:2]1[CH2:3][CH2:4][C:5]2([C:18]3[C:10](=[CH:11][C:12]4[CH2:13][CH2:14][N:15]([C:37]([C:34]5[CH:33]=[CH:32][C:31]([C:28]6[CH:29]=[CH:30][C:25]([C:22]7[N:21]=[C:20]([CH3:19])[O:24][N:23]=7)=[CH:26][CH:27]=6)=[CH:36][CH:35]=5)=[O:38])[C:16]=4[CH:17]=3)[O:9][CH2:8]2)[CH2:6][CH2:7]1