1'-Methyl-6,7-dihydro-2H,5H-spiro[furo[2,3-f]indole-3,4'-piperidine] → 5-(4'-Acetyl-2'-methylbiphenyl-4-carbonyl)-1'-methyl-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidine]

Participants

Role	Name	HCID	Charge
Reactant	1'-Methyl-6,7-dihydro-2H,5H-spiro[furo[2,3-f]indole-3,4'-piperidine]	HCID 10657952	—
Reactant	4'-Acetyl-2'-methyl-[1,1'-biphenyl]-4-carboxylic acid	HCID 21833739	—
Product	5-(4'-Acetyl-2'-methylbiphenyl-4-carbonyl)-1'-methyl-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidine]	HCID 21833779	—

Reaction Steps

The title compound was prepared from 1'-methyl-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidine] (D8) and 4'-acetyl-2'-methylbiphenyl-4-carboxylic acid (D19) using a procedure similar to that of Example 1 (35%).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05972951
Source dataset	uspto-grants-1999_10
ORD ID	ord-df53e810f6b24c9e966c61e0f1fd9a62
Source note	uspto-grants-1999_10