HRID1741118

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COC(=O)c1ccc(-c2ccc(C(=O)O)cc2)c(C)c1

HCID21833799

4'-(Methoxycarbonyl)-2'-methyl[1,1'-biphenyl]-4-carboxylic acid

C16H14O4

HCID22115885

未命名化合物

PRODUCTS

生成物

结构：COC(=O)c1ccc(-c2ccc(C(=O)N3CCCc4cc5c(cc43)C3(CCN(C)CC3)CO5)cc2)c(C)c1

HCID21833729

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 2,3,5,6,7,8-hexahydro-1'-methylspiro[furo[2,3-g]quinoline-3,4'-piperidine] (D10) and 4'-methoxycarbonyl-2'-methylbiphenyl-4-carboxylic acid (D41) using a procedure similar to that of Example 1 (46%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6fcacae68b9d4c6c8a0e6314fa9b43df
来源数据集: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05972951
来源说明: uspto-grants-1999_10

反应 SMILES

[CH3:1][N:2]1[CH2:7][CH2:6][C:5]2([C:19]3[C:10](=[CH:11][C:12]4[CH2:13][CH2:14][CH2:15][NH:16][C:17]=4[CH:18]=3)[O:9][CH2:8]2)[CH2:4][CH2:3]1.[CH3:20][O:21][C:22]([C:24]1[CH:29]=[CH:28][C:27]([C:30]2[CH:35]=[CH:34][C:33]([C:36](O)=[O:37])=[CH:32][CH:31]=2)=[C:26]([CH3:39])[CH:25]=1)=[O:23]>>[CH3:1][N:2]1[CH2:7][CH2:6][C:5]2([C:19]3[C:10](=[CH:11][C:12]4[CH2:13][CH2:14][CH2:15][N:16]([C:36]([C:33]5[CH:34]=[CH:35][C:30]([C:27]6[CH:28]=[CH:29][C:24]([C:22]([O:21][CH3:20])=[O:23])=[CH:25][C:26]=6[CH3:39])=[CH:31][CH:32]=5)=[O:37])[C:17]=4[CH:18]=3)[O:9][CH2:8]2)[CH2:4][CH2:3]1