Bromide ion → 1-(6-Bromo-pyridin-2-ylmethyl)-3-(4-fluoro-3-methyl-benzoyl)-1H-quinolin-4-one

HRID 174121Notes

Reaction equation

HRID 174121 reaction equation
[Br-:26].[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[CH3:1][O:2][N:3]([C:4](=[O:5])[c:6]1[cH:7][n:8]([CH2:17][c:18]2[n:19][c:20]([Br:24])[cH:21][cH:22][cH:23]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][c:14]2[c:15]1=[O:16])[CH3:25].[F:27][c:28]1[c:29]([CH3:35])[cH:30][c:31]([Mg+:34])[cH:32][cH:33]1>>[C:4](=[O:5])([c:6]1[cH:7][n:8]([CH2:17][c:18]2[n:19][c:20]([Br:24])[cH:21][cH:22][cH:23]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][c:14]2[c:15]1=[O:16])[c:31]1[cH:30][c:29]([CH3:35])[c:28]([F:27])[cH:33][cH:32]1

Participants

5

Reactant 4

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 577545321-(6-Bromo-pyridin-2-ylmethyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid methoxy-methyl-amideHCID 178427977HCID 178427977, compound

Product 1

HCID 577546711-(6-Bromo-pyridin-2-ylmethyl)-3-(4-fluoro-3-methyl-benzoyl)-1H-quinolin-4-one

Sources & evidence

ORD record
ord-4e751a1e72a74b8ba190501b8987fb90
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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