4-Chlorophenol → 4-Chlorophenyl Acetate

HRID 1741220Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.[C:9](OC(=O)C)(=[O:11])[CH3:10]>>[C:9]([O:8][C:5]1[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=1)(=[O:11])[CH3:10]

Participants

Reactant 2

HCID 46844-Chlorophenol

HCID 7918Acetic Anhydride

Product 1

HCID 134104-Chlorophenyl Acetate

Procedure

4-Chlorophenyl acetate is prepared by acylation of 4-chlorophenol with acetic anhydride using Schotten Baumann conditions.

Sources & evidence

ORD record: ord-5b08d76439fe4151bfb7dcce551ef106
Source dataset: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05973075

Reaction notes

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