Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1741260Generated: November 1, 2026

Diethylformamide → 4,5,7-Trichloroquinoline

https://huagongshe.com/reaction/1741260

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethylformamideHCID 12051—
ReactantThionyl ChlorideHCID 24386—
ReactantHCID 178418458HCID 178418458—
SolventDimethylformamideHCID 6228—
Product4,5,7-TrichloroquinolineHCID 615835—

Reaction Steps

reacting 5,7-dichloro-4-hydoxyquinoline with thionyl chloride in the presence of N,N-dimethylformamide or N,N-diethylformamide to obtain 4,5,7-trichloroquinoline,

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05973153
Source datasetuspto-grants-1999_10
ORD IDord-632837123a594dd9a3d655f2584c17b1
Source noteuspto-grants-1999_10