Triphenylphosphine → HCID 86751814, compound

HRID 1741320Notes

Reaction equation

[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:11]([C:13]2[CH:18]=[CH:17][C:16]([C:19](=[N:21][O:22][CH2:23][CH2:24][OH:25])[CH3:20])=[CH:15][N:14]=2)[CH3:12])(=[O:10])=[O:9])=[CH:4][CH:3]=1.O[C:27]1[CH:59]=[CH:58][C:30]([CH2:31][CH:32]2[S:36][C:35](=[O:37])[N:34]([C:38]([C:51]3[CH:56]=[CH:55][CH:54]=[CH:53][CH:52]=3)([C:45]3[CH:50]=[CH:49][CH:48]=[CH:47][CH:46]=3)[C:39]3[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=3)[C:33]2=[O:57])=[CH:29][CH:28]=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.N(C(OCC)=O)=NC(OCC)=O>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:11]([C:13]2[CH:18]=[CH:17][C:16]([C:19](=[N:21][O:22][CH2:23][CH2:24][O:25][C:27]3[CH:59]=[CH:58][C:30]([CH2:31][CH:32]4[S:36][C:35](=[O:37])[N:34]([C:38]([C:51]5[CH:56]=[CH:55][CH:54]=[CH:53][CH:52]=5)([C:45]5[CH:46]=[CH:47][CH:48]=[CH:49][CH:50]=5)[C:39]5[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=5)[C:33]4=[O:57])=[CH:29][CH:28]=3)[CH3:20])=[CH:15][N:14]=2)[CH3:12])(=[O:9])=[O:10])=[CH:4][CH:3]=1

Participants

Reactant 4

HCID 11776Triphenylphosphine

HCID 220568ethyl N-ethoxycarbonyliminocarbamate

HCID 28181265-(4-Hydroxybenzyl)-3-triphenylmethylthiazolidine-2,4-dione

HCID 53844312HCID 53844312, compound

Product 1

HCID 86751814HCID 86751814, compoundYield 88%

Procedure

Following a procedure similar to that described in Example 1(a), but using 1.22 g of 2-(1-{2-[N-(4-methylphenylsulfonyl)-N-methylamino]pyridin-5-yl}ethylideneaminooxy)ethanol (prepared as described in Preparation 34), 1.52 g of 5-(4-hydroxybenzyl)-3-tritylthiazolidine-2,4-dione, 0.97 g of triphenylphosphine and 0.63 g of diethyl azodicarboxylate, 2.33 g of the title compound were obtained as a foam-like solid.

Sources & evidence

ORD record: ord-d76b381e72584875bde1b089ca640f16
Source dataset: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05972959

Reaction notes

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