Sodium Hydroxide → HCID 86754722, compound

Participants

Reaction Steps

To a solution of ethyl [3-[[2-(4,5-diphenyloxazol-2-yl)tetrahydrofuran-3-yl]methyl]phenoxy]acetate (560 mg) in ethanol (20 ml) was added 1N-NaOH solution (1.2 ml). After being stirred for 4 hours at the same temperature, the solvent was removed in vacuo to give sodium [3-[[2-(4,5-diphenyloxazol-2-yl)tetrahydrofuran-3-yl]methyl]phenoxy]-acetate (0.46 g) FABMS (m/z): 478 (M+ +1) IR (Nujol): 3400, 1600 cm-1NMR (DMSO-d6, δ): 1.6-3.0 (5H, m), 3.8-4.2 (4H, m), 4.68 (1/3H, d, J=7.0 Hz), 5.13 (2/3H, d, J=8.0 Hz), 6.6-6.8 (3H, m), 7.0 (1H, t, J=8 Hz), 7.2-7.8 (10H, m)

Provenance & Evidence