反应详情

To 15 ml of a saturated solution of hydrogen chloride in ether, there were added 10 ml of acetone and 1.30 g (4.4 mmol) of N-(2-hydroxy-4-methylphenyl)-3-(tert-butoxycarbonyl)aminopropionamide and stirred at room temperature for 30 minutes. After the completion of the reaction, the crystals thus precipitated were filtered, washed with ether and dried. Thus 0.76 g (2.6 mmol) of N-(2-hydroxy-4-methylphenyl)-3-aminopropionamide hydrochloride was obtained. The yield was 59%.

1. customAfter the completion of the reaction
2. customthe crystals thus precipitated
3. filtrationwere filtered
4. washwashed with ether
5. customdried