Dichloromethane → 7-[(1-acetylpiperidin-4-yl)methoxy]-4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxyquinazoline
Reaction equation
[CH2:46]([Cl:47])[Cl:48].[CH3:42][C:43]([Cl:44])=[O:45].[CH:33]([N:34]([CH:35]([CH3:36])[CH3:37])[CH2:38][CH3:39])([CH3:40])[CH3:41].[F:1][c:2]1[c:3]2[cH:4][c:5]([CH3:32])[nH:6][c:7]2[cH:8][cH:9][c:10]1[O:11][c:12]1[n:13][cH:14][n:15][c:16]2[cH:17][c:18]([O:24][CH2:25][CH:26]3[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]3)[c:19]([O:22][CH3:23])[cH:20][c:21]12>>[F:1][c:2]1[c:3]2[cH:4][c:5]([CH3:32])[nH:6][c:7]2[cH:8][cH:9][c:10]1[O:11][c:12]1[n:13][cH:14][n:15][c:16]2[cH:17][c:18]([O:24][CH2:25][CH:26]3[CH2:27][CH2:28][N:29]([C:43]([CH3:42])=[O:45])[CH2:30][CH2:31]3)[c:19]([O:22][CH3:23])[cH:20][c:21]12Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-468ed124cf3f45febaaf30ddf1234759
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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