HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Chloride → HCID 22392078, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | 2-(Trifluoromethyl)-1,3-thiazole-4-carbaldehyde | HCID 20086717 | — |
| Reactant | HCID 178418486 | HCID 178418486 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 22392078 | HCID 22392078 | — |
Reaction Steps
11 cm3 of a molar solution of ethynyl magnesium bromide is added to a solution of tetrahydrofuran containing 2 g of 2-(trifluoromethyl) 4-thiazolecarboxaldehyde. The reaction mixture is kept under agitation for 30 minutes at 20°/25° C. then it is poured into an ammonium chloride solution. Extraction is carried out with methylene chloride, the extracts are dried, filtered and brought to dryness. 2.1 g of desired product is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05336670 |
| Source dataset | uspto-grants-1994_08 |
| ORD ID | ord-18d0c6a4a2fd41a38f09f4a1f839a06a |
| Source note | uspto-grants-1994_08 |